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Genome-wide CRISPR screen in HeLa HMGCR-Clover cells

NIAID Data Ecosystem2026-05-26 收录

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数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP151225 数据链接链接失效反馈

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资源简介：

This screen was designed to determine gene products involved in the sterol-induced degradation of HMGCR.

应用场景：

创建时间：

2018-12-13

胆固醇代谢调控

脂质稳态

In cell models, changes in the “accessible” pool of plasma membrane (PM) cholesterol are linked with the regulation of ER sterol synthesis and metabolism by the Aster family of nonvesicular transporte

NIAID Data Ecosystem90

MOESM1 of The intestinal microbiota regulates host cholesterol homeostasis

微生物组

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Additional file 1: Table S1. Datapoints for Fig. 1.

Figshare2019-11-28 更新60

STING OPS: HeLa Genome-wide Screen Single-Cell Features (Part 1/5)

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Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening Single-cell features and coordinates for HeLa genome

Zenodo2024-07-03 更新30

Supplementary Table 8 from Immunotherapy Inhibits Tumor Cholesterol Synthesis via the IFNγ–IRF1–SREBF2 Axis

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胆固醇代谢调控

Supplementary Table 8. The RNA-sequencing data of B16 tumors with anti-PD-1 treatment

Figshare2026-03-04 更新70

Data sheet index below 1.

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In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a

Figshare2022-09-22 更新50

Genome-wide CRISPR screen in HeLa HMGCR-Clover cells

资源简介：

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