Processes which may contribute to MDR over-representation.

NIAID Data Ecosystem2026-03-11 收录

多药耐药机制

数据链接：

https://figshare.com/articles/dataset/Processes_which_may_contribute_to_MDR_over-representation_/8120621 数据链接链接失效反馈

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Processes which may contribute to MDR over-representation.

创建时间：

2019-05-13

Structure of HIV-1 RT Q151M mutant

HIV逆转录酶结构解析

多药耐药机制

Structure of HIV-1 RT Q151M mutant Descriptor: RT p51 subunit, RT p66 subunit Authors: Nakamura, A, Tamura, N, Yasutake, Y. Deposit date: 2015-04-27 Release date: 2015-11-11 Last modified: 2023-11-08

Protein Data Bank Japan2023-11-08 更新60

The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 resolution

蛋白质晶体

多药耐药机制

The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 resolution Descriptor: MERCURY (II) ION, multidrug resistance protein, octyl beta-D-glucopyr

Protein Data Bank Japan2024-05-29 更新30

FBXW7

多药耐药机制

肿瘤靶向治疗

Purpose: FBXW7 is one of the most frequently mutated tumor suppressors, the deficiency of which has been associated with resistance to some anticancer therapies. Through bioinformatic analyses and gen

NIAID Data Ecosystem20

Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance. Homo sapiens

多药耐药机制

MicroRNA调控

Multidrug resistance (MDR) frequently develops in cancer patients exposed to chemotherapeutic agents and is usually brought about by over-expression of P-glycoprotein (P-gp) which acts as a drug efflu

NIAID Data Ecosystem60

Kinetic Validation of the Models for P-Glycoprotein ATP Hydrolysis and Vanadate-Induced Trapping. Proposal for Additional Steps

P-糖蛋白动力学建模

多药耐药机制

P-Glycoprotein, a member of the ATP-binding cassette (ABC) superfamily, is a multidrug transporter responsible for cellular efflux of hundreds of structurally unrelated compounds, including natural pr

NIAID Data Ecosystem30

Processes which may contribute to MDR over-representation.

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