Subregion specific dynamics of striatal dopamine

Transient increases in dopamine within the striatum can encode reward prediction errors, critical signals for updating predictions of future rewards. However, it is unclear how this mechanism can provide suitable feedback for predictions across a wide range of time horizons: from seconds or less (if singing a song) to potentially hours or more (if hunting for food). Here we report that dopamine transients in distinct striatal subregions convey prediction errors over distinct time scales. Dopamine dynamics systematically accelerated from ventral to dorsal- medial to dorsal-lateral striatum, in the tempo of their spontaneous fluctuations, their temporal integration of prior rewards, and their discounting of future rewards. This spectrum of time scales for evaluative computations can help achieve efficient learning and adaptive motivation for a wide range of behaviors.

, , , # Subregion Specific Dynamics of Striatal Dopamine

## Description of the data and file structure

The dataset included in this repository follows the standard format used by the Berke lab. It contains the necessary files and data required to replicate the experiments and findings described in the research article. Additionally, we have provided MATLAB code that can be utilized to read and interpret the data, as well as generate figures related to our results.

The dataset consists of three *.zip files. Each zip file contains MATLAB/python scripts and data files required to reproduce the graphs in corresponding figures. Following is the description for each data file.

### **Fig2.zip**:

**This text contains data and MATLAB scripts to replicate Fig2. The data is saved in .mat format, which can be loaded in MATLAB as a 1x41 struct. Each struct has recordings from one behavioral session of the bandit task and has these elements:**

* **Fs:** Sampling Frequency of the photometry signa...