The cure rate for late stage epithelial ovarian cancer (EOC) has not significantly improved over several decades. New and more effective targets and treatment modalities are urgently needed. RNA-seq a

NIAID Data Ecosystem50

CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling

卵巢癌分子机制

NF-κB信号通路

Ovarian cancer is an inflammation-associated malignancy with a high mortality rate. CXCR2 expressing ovarian cancers are aggressive with poorer outcomes. We therefore investigated molecular mechanisms

NIAID Data Ecosystem30

Additional file 2 of Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression

卵巢癌分子机制

基因功能研究

Additional file 2: Table 1. KBTBD8 shRNA information. This table shows all the sequences and locations of human KBTBD8 shRNAs used in this study. shRNAs were cloned into the plasmid GV248 cutted by Ag

NIAID Data Ecosystem60

Supplementary Table 1a from miR-450a Acts as a Tumor Suppressor in Ovarian Cancer by Regulating Energy Metabolism

卵巢癌分子机制

miRNA靶标预测

Supplementary Table 1a. List of potential total miRNA and miR-450a only binding sites from A2780 control cell line

NIAID Data Ecosystem50