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Transformation of the Fallopian Tube Secretory Epithelium Leads to High-grade Serous Ovarian Cancer in BRCA/P53/PTEN Models

ChEBI2013-12-17 更新2026-07-21 收录

卵巢癌分子机制

基因模型病理研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-49827 数据链接链接失效反馈

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资源简介：

Transformation of the Fallopian Tube Secretory Epithelium Leads to High-grade Serous Ovarian Cancer in BRCA/P53/PTEN Models

应用场景：

创建时间：

2013-12-17

卵巢癌分子机制

基因功能研究

Additional file 2: Table 1. KBTBD8 shRNA information. This table shows all the sequences and locations of human KBTBD8 shRNAs used in this study. shRNAs were cloned into the plasmid GV248 cutted by Ag

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CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling

卵巢癌分子机制

NF-κB信号通路

Ovarian cancer is an inflammation-associated malignancy with a high mortality rate. CXCR2 expressing ovarian cancers are aggressive with poorer outcomes. We therefore investigated molecular mechanisms

NIAID Data Ecosystem30

WP3303 - RAC1/PAK1/p38/MMP2 pathway - Homo sapiens

癌症信号通路

卵巢癌分子机制

Interplay of RAC1, p38 MAPK, PAK1 and MMP2 in cell signaling pathways downstream of TEK receptor activity related to tumor growth, angiogenesis, and cell proliferation. These processes are reduced in

NIAID Data Ecosystem20

Changes in mRNA/protein expression and signaling pathways in in vivo passaged mouse ovarian cancer cells

卵巢癌分子机制

肿瘤RNA-seq分析

The cure rate for late stage epithelial ovarian cancer (EOC) has not significantly improved over several decades. New and more effective targets and treatment modalities are urgently needed. RNA-seq a

NIAID Data Ecosystem50

Expression data from TGF-beta-treated human ovarian fibroblasts. Homo sapiens

肿瘤微环境

卵巢癌分子机制

Advanced ovarian cancer is the most lethal gynecologic malignancy in the United States. Ovarian cancer cells are known to have diminished response to TGF-beta, but it remains unclear whether TGF-beta

NIAID Data Ecosystem20

Transformation of the Fallopian Tube Secretory Epithelium Leads to High-grade Serous Ovarian Cancer in BRCA/P53/PTEN Models

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