Copper-Catalyzed Formal [4 + 1] Cycloaddition of Benzamides and Isonitriles via Directed C–H Cleavage
收藏NIAID Data Ecosystem2026-03-08 收录
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资源简介：
A copper-catalyzed formal [4 + 1] cycloaddition of benzamides and isonitriles via 8-aminoquinoline-directed C–H cleavage has been developed. The reaction proceeds well even in the presence of a base metal catalyst, CuBr·SMe2, alone to deliver the corresponding 3-iminoisoindolinones in good yields. Moreover, the unique acceleration effects of diphenyl sulfide are also disclosed.
创建时间：
2015-08-21
