Identification of differentially expressed fecal miRNA in hepatic encephalopathy

To further identify the fecal miRNAs generated in HE, we conducted an miRNA microarray analysis on feces collected from patients with HE and CHB. The microarray analysis of miRNA expression profiles revealed that the abundance of 10 miRNAs was significantly increased in feces from patients with HE, as compared with that from patients with CHB, whereas the abundance of 8 miRNAs was decreased. RNA was isolated from feces of 2 patients with HE and 2 patients with CHB.