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Integration of epigenetic and transcriptional mechanisms governs functional commitment versus plasticity of gd T cell subsets

ChEBI2013-09-01 更新2026-07-21 收录

γδT细胞分化

表观转录调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42098 数据链接链接失效反馈

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Integration of epigenetic and transcriptional mechanisms governs functional commitment versus plasticity of gd T cell subsets

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创建时间：

2013-09-01

γδT细胞分化

转录因子调控

Innate-like gd T effector subsets are exported from the thymus as “memory-like” cells prewired for rapid, specialized function. Previously, we showed that emergent gd subsets distinguished by TCRg and

NIAID Data Ecosystem80

A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription [ChIP-seq]. A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription [ChIP-seq]

表观转录调控

tRNA甲基化

Since numerous RNAs and RBPs prevalently localize to active chromatin regions, many RNA binding proteins (RBPs) may be potential transcriptional regulators. RBPs are generally thought to regulate tran

NIAID Data Ecosystem40

A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription [CLIP-seq]

tRNA甲基转移酶功能

表观转录调控

NIAID Data Ecosystem30

c-Maf is an essential commitment factor for IL-17-producing gd T cells

γδT细胞分化

IL-17免疫调控

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem60

Table_2_Sonic Hedgehog Is a Determinant of γδ T-Cell Differentiation in the Thymus.DOCX

γδT细胞分化

Hedgehog信号通路

Here we investigate the function of Hedgehog (Hh) signaling in thymic γδ T-cell maturation and subset differentiation. Analysis of Hh mutants showed that Hh signaling promotes γδ T-cell development in

NIAID Data Ecosystem30

Integration of epigenetic and transcriptional mechanisms governs functional commitment versus plasticity of gd T cell subsets

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