Structure of KRAS G12C bound to Compound 4
收藏Protein Data Bank Japan2026-03-25 更新2026-04-19 收录
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Structure of KRAS G12C bound to Compound 4 Descriptor: 1-(4-{(7M)-7-[6-amino-3-(trifluoromethyl)pyridin-2-yl]-6-chloroquinazolin-4-yl}piperazin-1-yl)propan-1-one, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... Authors: Kiefer, J.R, Wang, W, Oh, A, Yu, C. Deposit date: 2025-08-11 Release date: 2026-03-11 Last modified: 2026-03-25 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C. J.Med.Chem., 69, 2026
创建时间：
2025-08-11
