Heart development
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This pathway has been largely adapted from an article by Deepak Srivastava, Cell. 2006 Sep 22;126(6):1037-48. In this pathway are known transcription factors, miRNAs and regulatory proteins that impact the regional specificity of the human heart. Activating signals are indicated by arrows while inhibitory signals are indicated by T-bars. Special thanks to Kim Cordes for her assistance in revising this pathway, based on recent heart development research.
本路径主要改编自Deepak Srivastava发表于《Cell》杂志的论文,发表于2006年9月22日的第126卷第6期,即第1037-1048页。该路径中包含已知转录因子、miRNA和调控蛋白,这些成分对人类心脏区域特异性产生显著影响。激活信号以箭头表示,而抑制信号则以T形条表示。特别感谢Kim Cordes对修订本路径的帮助,该修订基于最新的心脏发育研究。
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