Data underlying the publication: Co-translational ribosome pairing enables native assembly of misfolding-prone subunits

This dataset contains data collected during correlated single-molecule force spectroscopy and multi-color confocal laser scanning spectroscopy experiments at AMOLF, as part of Katharina Till's PhD Thesis project. The objective of the project behind this data was to use disome selective ribosome profiling (DiSP) to detect co-translational assembly of the intermediate filament lamin in vivo and optical tweezers are to study folding and assembly transitions for individual monomers and dimers in vitro. The data included in this data set has been organised per figure of the corresponding to be published publication. The excel sheet contains several tabs containing the underlying data to the figures they are named after. The data is being made public both to act as supplementary data for publications and the PhD thesis of Katharina Till and in order for other researchers to use this data in their own work.

本数据集包含荷兰原子与分子物理研究所（AMOLF）开展的关联单分子力谱（single-molecule force spectroscopy）与多色共聚焦激光扫描光谱（multi-color confocal laser scanning spectroscopy）实验采集的数据，属于Katharina Till的博士学位论文研究项目的一部分。该项目的研究目标为利用二核糖体选择性核糖体谱分析（disome selective ribosome profiling, DiSP）在活体内检测中间丝核纤层蛋白的共翻译组装，同时借助光镊（optical tweezers）技术在体外对单个单体与二聚体的折叠及组装转变过程开展研究。本数据集已按照该待发表论文中的各幅图表进行分类整理，其中的Excel文件包含多个工作表，各工作表以其对应的图表命名，存储对应图表的原始数据。本次公开本数据集，既可为相关学术论文及Katharina Till的博士学位论文提供补充数据，也可供其他科研人员在自身研究中复用该数据。