NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
收藏reactome.org2025-01-22 收录
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Based on studies in rat neurons, the NF-Y transcription factor complex (composed of NFYA, NFYB and NFYC) and histone acetyltransferases EP300 (p300) and/or CREBBP (CBP) constitutively bind to evolutionarily conserved sites in the promoter of the BCL2L11 (BIM) gene (Hughes et al. 2011).
基于对大鼠神经元的研究,NF-Y转录因子复合物(由NFYA、NFYB和NFYC组成)以及组蛋白乙酰转移酶EP300(p300)和/或CREBBP(CBP)在进化上保守的BCL2L11(BIM)基因启动子区域呈组成性结合(参见Hughes等,2011年)。
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