Structure of human Bruton's Tyrosine Kinase in complex with Evobrutinib
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Structure of human Bruton's Tyrosine Kinase in complex with Evobrutinib Descriptor: 1-[4-({[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino}methyl)piperidin-1-yl]prop-2-en-1-one, CHLORIDE ION, Tyrosine-protein kinase BTK Authors: Mochalkin, I, Gardberg, A.S. Deposit date: 2019-04-19 Release date: 2019-08-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases. J.Med.Chem., 62, 2019
创建时间：
2019-04-19
