Data from: Meiotic drive reduces egg-to-adult viability in stalk-eyed flies

A number of species are affected by sex ratio meiotic drive (SR), a
selfish genetic element located on the X chromosome that causes
dysfunction of Y-bearing sperm. SR is transmitted to up to 100% of
offspring, causing extreme sex ratio bias. SR in several species is found
in a stable polymorphism at a moderate frequency, suggesting there must be
strong frequency-dependent selection resisting its spread. We investigate
the effect of SR on female and male egg-to-adult viability in the
Malaysian stalk-eyed fly, Teleopsis dalmanni. SR meiotic drive in this
species is old, and appears to be broadly stable at a moderate (~20%)
frequency. We use large-scale controlled crosses to estimate the strength
of selection acting against SR in female and male carriers. We find that
SR reduces the egg-to-adult viability of both sexes. In females,
homozygous females experience greater reduction in viability (sf = 0.242)
and the deleterious effects of SR are additive (h = 0.511). The male
deficit in viability (sm = 0.214) is not different from that in homozygous
females. The evidence does not support the expectation that deleterious
side-effects of SR are recessive or sex-limited. We discuss how these
reductions in egg-to-adult survival, as well as other forms of selection
acting on SR, may maintain the SR polymorphism in this species.