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VCAM-1 in atherosclerotic macrophages

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE207634
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We identified the genes regulated by VCAM-1 in atherosclerotic macrophages. We selected some of these genes based on their expression and further evaluated their functions using a wide array of techniques. Bone marrow chimeric Ldlr KO mice were generated by transplanting LysM+/+ Vcam1fl/fl or LysMcre/+ Vcam1fl/fl bone marrow. We sorted macrophages from atherosclerotic plaques of these mice. mRNA was extracted from these samples and bulk RNA sequencing was performed.
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2024-04-28
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