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Enteroendocrine cell lineages that differentially control feeding and gut motility

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Enteroendocrine cells (EECs) are specialized sensory cells of the gut-brain axis that are sparsely distributed along the intestinal epithelium. Intestinal EECs of Ngn3-Cre;tdTom and NeuroD1-Cre;tdTom mice were isolated by Fluorescence-activated cell sorting (FACS) according to the presence or absence of tdTomato signal and analyzed using scRNAseq.

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