Expression data from WT and Snail1 knockout (KO) embryonic endothelial cells (ECs). Mus musculus

Snail1 is a master factor of epithelial to mesenchymal transitioin (EMT), however, its role in embryonic vascular development is largely undefined. We used microarrays to compare the global programme of gene expression between cultured WT and Snai1 KO embyronic ECs. Overall design: ECs isolated from E10.5 Snail1f/f embryos were infected with adeno-βGal or -Cre to generate WT and Snail1 KO ECs. RNA were collected for Affymetrix microarrays.