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Structure of pregnane X receptor in complex with a Sphingosine 1- Phosphate Receptor 1 Antagonist

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Structure of pregnane X receptor in complex with a Sphingosine 1- Phosphate Receptor 1 Antagonist Descriptor: 4-chloro-N-[(1R)-1-[1-ethyl-6-(trifluoromethyl)benzimidazol-2-yl]ethyl]benzenesulfonamide, NUCLEAR RECEPTOR COACTIVATOR 1, NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 Authors: Xue, Y, Oster, L. Deposit date: 2015-07-13 Release date: 2015-10-21 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity. J.Med.Chem., 58, 2015
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2015-07-13
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