Additional file 2 of Dysregulated lipid metabolism in a retinal pigment epithelial cell model and serum of patients with age-related macular degeneration

Additional file 2: Tables S2–S5. Table S2 Small molecules detected and identified in positive ionization mode. A total of 185 compounds where tentatively identified using ID browser, showing the normalized averaged data for each of the tentatively identified compounds. Table S3 Small molecules detected and identified in negative ionization mode. A total of 68 compounds where tentatively identified using ID browser, showing the normalized averaged data for each of the tentatively identified compounds. Table S4 Demographic characteristics of AMD patients (n = 20) and control subjects (n = 20). Table S5 Comparison of selected lipids levels in serum samples from control (n = 20) and AMD patients (n = 20). Lipid levels were normalized to the sample volume and expressed as the mean ± standard deviation across 20 biological replicates for each group. Group comparisons were conducted using the Mann–Whitney or unpaired t-test, depending on data distribution normality assessed via the Kolmogorov–Smirnov test. To account for multiple comparisons, p values were adjusted using the Benjamini–Hochberg method. Statistical significance is indicated as follows: ns: adjusted p value > 0.05; *: adjusted p value < 0.05; **: adjusted p value < 0.01; ***: adjusted p value < 0.001.