CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis. CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis

To study the differential expression of genes in prostate cancer tissue and benign prostatic hyperplasia Overall design: Microarray hybridization analysis of mRNA expression in two PCa samples and two benign prostatic hyperplasia tissues were performed according to the manufacturer’s protocol (Arraystar, Inc., Rockville, MD, USA).