Pd/NHC-Catalyzed Enantiospecific and Regioselective Suzuki–Miyaura Arylation of 2‑Arylaziridines: Synthesis of Enantioenriched 2‑Arylphenethylamine Derivatives
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https://figshare.com/articles/dataset/Pd_NHC_Catalyzed_Enantiospecific_and_Regioselective_Suzuki_Miyaura_Arylation_of_2_Arylaziridines_Synthesis_of_Enantioenriched_2_Arylphenethylamine_Derivatives/2281654
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资源简介：
A palladium-catalyzed
stereospecific and regioselective cross-coupling
of enantiopure 2-arylaziridines with arylboronic acids under mild
conditions to construct a tertiary stereogenic center has been developed.
N-heterocyclic carbene (NHC) ligands efficiently promote the coupling,
suppressing β-hydride elimination. The enantiospecific cross-coupling
allowed us for preparation of a series of biologically important 2-arylphenethylamine
derivatives in an enantiopure form.
创建时间：
2016-02-17
