RNAseq analysis of Saccharomyces cerevisiae ethanol fermentation with oxygen sparging during the fermentation phase provided by either microbubbles or regular bubbles

Microbubbles are micron-sized bubbles generated using a fluidic oscillator. They have the potential to decrease the cost of biotechnology processes through decreasing the energy required for aeration and mixing. Propagation of yeast cells showed few morphological and transcriptomic changes when cultivated with either micro bubbles or regular bubbles. This experiment was designed to see if changes could be detected in the transcriptome when cells were cultivated on microbubbles and then split into two reactors for the fermentation phase where low levels of oxygen were provided during the fermentation phase using either micro bubbles or regular bubbles