Long noncoding RNAs (lncRNAs) are widely dysregulated in cancer, yet their functional roles in cellular disease hallmarks remain unclear. Here we employ pooled CRISPR deletion to perturb 831 lncRNAs d

NIAID Data Ecosystem70

Identification of targets specifically regulated by a 'super hybrid p53'. Homo sapiens

肿瘤抑制蛋白功能

癌症靶点筛选

p63, like its homologue, the tumor suppressor p53, is also able to induce apoptosis in several cancer cell types. p53 family proteins are composed of three characteristic domains which are: 1) an N-te

NIAID Data Ecosystem30

Additional file 2: Table S3. of Identification of therapeutic targets applicable to clinical strategies in ovarian cancer

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基因功能验证

Candidate shRNAs identified in Ovcar5. (XLS 426Â kb)

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