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Crystal structure of TL11-113 bound to TAK1-TAB1

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of TL11-113 bound to TAK1-TAB1 Descriptor: Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide Authors: Gurbani, D, Westover, K.D. Deposit date: 2016-04-07 Release date: 2017-02-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.404 Å) Cite: Structure-guided development of covalent TAK1 inhibitors. Bioorg. Med. Chem., 25, 2017
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2016-04-07
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