Identification of ALS Associated Genes Using Whole Genome Sequencing

The overall aim of this study is to discover of novel genetic elements associated with amyotrophic lateral sclerosis (ALS). Towards this goal, we have performed exome and whole genome sequencing for over 2000 samples. This data will be process and harmonized to yield high quality variant calling. These variants will be combined with control cohorts to identify novel genetic elements associated with ALS through case: control analyses.]]>
Inclusion CriteriaAll cases have either Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), or other neurological disease.All controls were subjects without a neurological disease. ]]>