Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells.

Data from ProteomeXchange, PXD ID: PXD001078. File: folder summary. Published as part of J Proteome Res. 2015 Feb 6;14(2):1250-62 . From the Abstract: {{i}} ... Treatment of triple-negative breast cancer (TNBC) is complex and challenging, especially when metastasis has developed. In this study, we applied infrared radiation as an alternative approach for the treatment of TNBC. We used middle infrared (MIR) with a wavelength range of 3-5 microns to irradiate breast cancer cells. MIR significantly inhibited cell proliferation in several breast cancer cells but did not affect the growth of normal breast epithelial cells. We performed iTRAQ-coupled LC-MS/MS analysis to investigate the MIR-triggered molecular mechanisms in breast cancer cells ... {{/i}}