Single cell multi-omic data of glioblastoma evolution under therapy
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001004909
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资源简介：
We report a single-cell multi-omics atlas of GBM longitudinal specimens that represents decades of biobanking. We identify novel cell-intrinsic and cell-extrinsic targets for therapy development which we validate in situ and in low-passage patient-derived cell lines. We identify novel genetic correlates of the mesenchymal cellular phenotype. These studies integrate disparate findings in the literature around
hypermutation status and immunogenicity as well as the source of the mesenchymal shift at recurrence.EGA study EGAS00001004909
创建时间：
2022-09-19
