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Analysis of the effect of TSLP stimulated CD4+T cells on epigenetic markers in PyMT primary tumors

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP277218
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资源简介:
TSLP-stimulated CD4+ T cells block the promotion of breast cancer in a spontaneous PyMT mouse model. The goal of this project is to investigate what are the epigenetic changes induced by CD4+ T cells that lead to diminished proliferation of cancer cells Overall design: K14-TSLPtg;PyMT;Rag1KO, and PyMT;Rag1KO mice were injected with wt CD4+ T cells at 4 weeks of age. Tumors were collected when they reached terminal size and tissue was processed for ChIP seq analysis.
创建时间:
2022-06-25
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