sciPlex dataset
收藏资源简介:
<i>Transcriptomes of 650000 A549, K562, and mCF7 cells exposed to 188 compounds.</i><br><br><i> sci-Plex was used to screen three well-characterized human cancer cell lines, A549</i><br><i> (lung adenocarcinoma), K562 (chronic myelogenous leukemia), and MCF7 (mammary</i><br><i> adenocarcinoma)exposed to 188 compounds, profiling ~650,000 single-cell</i><br><i> transcriptomes across ~5000 independent samples in one experiment.</i><br><br><i> References:</i><br><i> Publication: https://doi.org/10.1126/science.aax6234 \</i><br><i> Obtained from scperturb: http://projects.sanderlab.org/scperturb/</i>
650,000个经188种化合物处理的A549、K562及mCF7细胞的转录组(transcriptome)。 本研究采用sci-Plex技术,对三种经过充分表征的人源癌细胞系展开筛选:A549细胞(肺腺癌细胞)、K562细胞(慢性髓系白血病细胞)以及MCF7细胞(乳腺腺癌细胞),将其暴露于188种化合物中,并在单次实验中对约5000个独立样本的约65万个单细胞转录组进行了分析。 参考文献: 发表文献:https://doi.org/10.1126/science.aax6234 数据来源:scperturb数据库:http://projects.sanderlab.org/scperturb/




