Fragment-Based Discovery of a Novel Bruton's Tyrosine Kinase Inhibitor
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Fragment-Based Discovery of a Novel Bruton's Tyrosine Kinase Inhibitor Descriptor: 1,2-ETHANEDIOL, 5-(1H-benzimidazol-2-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, IMIDAZOLE, ... Authors: Dougan, D.R, Lawson, J.D. Deposit date: 2021-06-06 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 ( S )-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3 H -1,2,4-triazol-3-one, by Fragment-Based Drug Design. J.Med.Chem., 64, 2021
创建时间：
2021-06-06
