Synthesis of Optically Active Organofluorides by Ring Opening of Oxazolidinone-Fused Aziridines
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https://figshare.com/articles/dataset/Synthesis_of_Optically_Active_Organofluorides_by_Ring_Opening_of_Oxazolidinone-Fused_Aziridines/21786775
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资源简介:
A general method for synthesizing
optically active, primary, secondary,
and tertiary organofluorides was developed. This chiral pool synthesis
utilized the skeleton of arabinose to generate diastereomerically
pure 2-oxazolidinone-fused aziridines, which underwent ring opening
with a fluoride anion. The adducts, polyoxygenated organofluorides,
were useful precursors to various fluorinated compounds, such as fluorinated
amino acids.
创建时间:
2022-12-28



