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Role of N-a-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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We report that Naa10-null mice display partial embryonic lethality, growth retardation, brain disorder and maternal-effect lethality, phenotypes commonly observed in defective genomic imprinting. Genome-wide analyses further reveal enriched dysregulation of imprinted genes in Naa10p-knockout ES cells.

提供机构:
Academia Sinica
创建时间:
2022-02-20
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