Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota

Data repository for: Wu RY, Määttänen P, Napper S, Scruten E, Li B, Koike Y, Johnson-Henry KC, Pierro A, Rossi L, Botts SR, Surette MG, Sherman PM. Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota. Microbiome. 2017;5:135. Available at: https://doi.org/10.1186/s40168-017-0357-4Repository information: PSWY FASTQ sequence files - 16S rRNA gene sequence files for P10 mice exposed to lipopolysaccharide (LPS) and non-digestible oligosaccharides (inulin and scFOS) 16S_metadata.txt - describes 16S rRNA gene sequence files 16S_preprocessed_sequences.fna - preprocessed sequence file for 16S rRNA gene data (quality filtering, chimera checking, etc.) 16S_otu_table_host_singleton_filtered_unrarified.biom - OTU table for 16S rRNA gene sequence analysis before rarefaction 16S_otu_table_host_singleton_filtered_sd9194.biom - OTU table for 16S rRNA gene sequence analysis after rarefaction to 9,194 OTU counts/sample 16S_PICRUSt_analysis_code.txt - commands for PICRUSt functional metagenome prediction kinome_array_data.txt - raw kinome array data for Caco-2Bbe1 cells exposed to non-digestible oligosaccharides (inulin and scFOS) and challenged with enterohemorrhagic Escherichia coli (EHEC) kinome_array_metadata.txt - describes raw kinome array data kinome_array_PIIKA_2_parameters.txt - PIIKA 2 parameters for kinome array analysis