Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.
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Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine. Descriptor: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ... Authors: Mamat, B, Davies, D.R. Deposit date: 2008-12-09 Release date: 2010-01-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis. J.Med.Chem., 53, 2010
创建时间:
2008-12-09



