Xeva_PDXE

PDXE XevaSet generated by ORCESTRA. Metadata can be found on ORCESTRA at: http://www.orcestra.ca/xevaset/10.5281/zenodo.4302463

Disclaimer

The PDXE data were generated and shared by the Sellers lab at The Broad Institute. The Haibe-Kains Lab has re-annotated the data to maximize overlap with other toxicogenomic datasets.

Data Usage Policy

Please note: The data files are experimental and academic in nature and are not licensed or certified by any regulatory body.

Please cite the following when using these data

Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, Zhang C, Schnell C, Yang G, Zhang Y, Balbin OA, Barbe S, Cai H, Casey F, Chatterjee S, Chiang DY, Chuai S, Cogan SM, Collins SD, Dammassa E, Ebel N, Embry M, Green J, Kauffmann A, Kowal C, Leary RJ, Lehar J, Liang Y, Loo A, Lorenzana E, Robert McDonald E 3rd, McLaughlin ME, Merkin J, Meyer R, Naylor TL, Patawaran M, Reddy A, Röelli C, Ruddy DA, Salangsang F, Santacroce F, Singh AP, Tang Y, Tinetto W, Tobler S, Velazquez R, Venkatesan K, Von Arx F, Wang HQ, Wang Z, Wiesmann M, Wyss D, Xu F, Bitter H, Atadja P, Lees E, Hofmann F, Li E, Keen N, Cozens R, Jensen MR, Pryer NK, Williams JA, Sellers WR. High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response. Nat Med. 2015 Nov;21(11):1318-25. doi: 10.1038/nm.3954. Epub 2015 Oct 19. PMID: 26479923.

Arvind S. Mer, Wail Ba-Alawi, Petr Smirnov, Yi X. Wang, Ben Brew, Janosch Ortmann, Ming-Sound Tsao, David W. Cescon, Anna Goldenberg and Benjamin Haibe-Kains. (2019) Integrative Pharmacogenomics Analysis of Patient-Derived Xenografts. Cancer Res September 1 2019 (79) (17) 4539-4550; DOI: 10.1158/0008-5472.CAN-19-0349.