Prediction of MMR achievement at 12 months with the use of different EMR markers.

We compared the ability 3 early molecular response (EMR) markers recently described (transcript level at 3 months, Halving time and transcript log reduction) to accurately predict the achievement of major molecular response (MMR) after 12 months of treatment, either with the use of ABL1 or GUS as control gene. Optimal cut-off for each marker was identified by using receiver operating characteristic (ROC) curve. Relative risks are expressed as odds ratios (OR) with 95% confidence interval (95% CI).Prediction of MMR achievement at 12 months with the use of different EMR markers.