Inflammatory response in HSPC of PTPN11-mutated JMML
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
Activating mutations in PTPN11 gene are the most frequent in JMML patients. Here we explore the transcriptome of HSPC (hematopoietic stem and progenitor cells) sorted from sporadic JMML patients with PTPN11 mutation and from healthy age matched donnors. Bulk transcriptome of sorted HSPC reveals an inflammatory gene expression signature which may represent a future target for JMML therapy. RNAseq data
创建时间：
2022-05-11
