Regenerated Cellulose Hydrogels as Bioaffinity Attachment Supports for Carbohydrate-Binding Module 1

Modification of cellulose hydrogels by choice of cellulose and regeneration solvent influences the surface area accessible to a family 1 carbohydrate-binding module, its affinity to the cellulose material and rate of migration through the hydrogel. The hydrogels may be used as support materials in bioaffinity applications but a compromise between accessible surface area and affinity, or migration rate, must be made.

通过对纤维素及其再生溶剂的选择性配伍，对纤维素水凝胶的改性将影响一类碳水化合物结合模块可接触的表面积、其对纤维素材料的亲和力以及通过水凝胶的迁移速率。此类水凝胶可用作生物亲和应用中的支撑材料，但在可接触表面积与亲和力、或迁移速率之间必须达成妥协。