Common lymphoid progenitor derivation of plasmacytoid dendritic cells is mediated by Bcl11a
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225768
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Plasmacytoid dendritic cells (pDC) specialize in type I interferon production to coordinate innate and adaptive immunity. We identify two pDC subsets in vivo, evaluate their genome-wide expression, and demonstrate a developmental requirement for Bcl11a to provide insight into this enigmatic cell type. Sorted Pdca1+ BM cells from WT naïve C57/BL6 mice and did 10x single cell seq
创建时间：
2024-10-08
