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Heterozygous and Homozygous Knock-Out of USP7 mouse models [mouse_RNA-seq]

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP256242
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RNAseq analysis of USP7 conditional knock-out (cKO) mice. They were designed to flox exon 6 of USP7 and to allow deletion of exon 6 upon expression of Cre recombinase 27. USP7FL/FL mice were bred with Vav1-Cre mice to obtain USP7FL/wt-Vav1-Cre mice (heterozygote). USP7FL/FL-Vav1-Cre mice (homozygote) were obtained via breeding of heterozygous cKO mice. Overall design: Single allele KO (n = 3), bi-allelic KO (n = 3), wild-type with cre-induced (n = 2), wild-type without cre-induction (n = 2)
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2026-01-10
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