O-atom dealkylation of dextromethorphan
收藏reactome.org2025-01-15 收录
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At the beginning of this reaction, 1 molecule of 'H+', 1 molecule of 'Dextromethorphan', 1 molecule of 'Oxygen', and 1 molecule of 'NADPH' are present. At the end of this reaction, 1 molecule of 'NADP+', 1 molecule of 'Dextrorphan', 1 molecule of 'Formaldehyde', and 1 molecule of 'H2O' are present.<br><br> This reaction takes place in the 'smooth endoplasmic reticulum' and is mediated by the 'oxygen binding activity' of 'Cytochrome P450 2D6 '.<br>
在该反应的初始阶段，存在1分子'H+'、1分子'右美沙芬'、1分子'氧气'以及1分子'NADPH'。在反应结束时，存在1分子'NADP+'、1分子'左美沙芬'、1分子'甲醛'以及1分子'水'。该反应发生于'平滑内质网'中，并由'细胞色素P450 2D6'的'氧气结合活性'所介导。
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