Crystal structure of Sirt2 in complex with selective inhibitor A2I
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of Sirt2 in complex with selective inhibitor A2I Descriptor: 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[3-(phenoxymethyl)phenyl]ethanamide, BETA-MERCAPTOETHANOL, NAD-dependent protein deacetylase sirtuin-2, ... Authors: Wang, H, Yu, Y, Li, G, Chen, Q. Deposit date: 2017-11-07 Release date: 2018-10-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.601 Å) Cite: X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells. Eur J Med Chem, 155, 2018
创建时间：
2017-11-07
