BPTF Depletion Enhances NK Cell Mediated Antitumor Immunity
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE85756
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资源简介：
In mouse models, the bromodomain PHD finger transcription factor (BPTF) chromatin remodeling subunit in tumor cells suppresses natural killer (NK) cell antitumor activity. In vitro, BPTF suppresses NK cell cytolytic activity to mouse and human cancer cell lines, demonstrating a conserved function. BPTF-depleted tumors from BALB/c or NSG mice were compared to control tumors using gene expresion microarray experiments.
创建时间：
2019-06-26
