Significant mQTL for GWAS of metabolite factors, race meta-analyses.

MAF: minor allele frequency; Add: additive model; Dom: dominant model.aW: white, B: black, O: other racebrace-stratified results sex, age and race-appropriate PC adjusted, and then combined using meta-analysis.cmeta-analysis combining discovery and validation cohorts, race-stratified results combined.Presented are SNPs meeting genomewide significance for association with factor 1 (MCA metabolites), factor 2 (LCDA metabolites) and factor 3 (SCDA metabolites) in race-combined meta-analyses in the discovery cohort (p≤10−6) also showing nominal association (p≤0.05) in the validation cohort, ranked by meta-analysis p-value.