Using RNAseq for identifying hepatic genes involved in multi- (F1 generation) and transgenerational (F2 generation) responses to chronic benzo[a]pyrene (BaP) and triclosan (TCS) mixture exposure (F0 generation) in Xenopus tropicalis.

We investigated the multi- and transgenerational impact of BaP and TCS mixture on Xenopus females following F0 generation exposure from the tadpole to the mature adult stage at a concentration (50 ng.L-1 each). 5 females from F1 and F2 generations by parentale exposure conditions (control vs Mixture) were used for studying liver transcriptome by RNAseq. RNA-seq libraries were sequenced on an illumina GAIIx sequencer as 75bp single reads Overall design: mRNAseq from liver of mature F1 and F2 females exposed to BaP and TCS mixture. Processed data file (Cuffdiff) have been performed by using RNAseq sequence from control mRNAseq data deposited on NCBI Gene Expression Omnibus (GEO) (accession no GSE150911)