PCOS summary statistics

This file contains data relating to the analysis discussed in "Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria." The data presented in this file is for the analysis of any diagnostic criteria, excluding the self-report based data from 23andMe. The file has the followin headers: MarkerName Effect_allele Other_allele EAF Effect [frd23@b08 PCOS]$ more PCOS_summary_data_19092018_README.txt This file contains data relating to the analysis discussed in "Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Su ggests Shared Genetic Architecture for Different Diagnosis Criteria." The data presented in this file is for the analysis of any diagnostic criteria, excluding the self-report based data from 23andMe. The file has the followin headers: MarkerName Effect_allele Other_allele EAF Effect StdErr Pvalue TotalSampleSize The data reported in this sheet has been truncated to 2 significant figures.

本文件包含与"大规模全基因组荟萃分析显示多囊卵巢综合征（Polycystic Ovary Syndrome，PCOS）不同诊断标准共享遗传结构"一文所讨论的分析相关的数据。本文件中呈现的数据适用于任意诊断标准的分析，但排除了来自23andMe的自我报告型数据。本文件的表头字段如下：标记名称（MarkerName）、效应等位基因（Effect_allele）、其他等位基因（Other_allele）、等位基因频率（EAF）、效应值（Effect）[frd23@b08 PCOS]$ more PCOS_summary_data_19092018_README.txt 本文件包含与"大规模全基因组荟萃分析显示多囊卵巢综合征（Polycystic Ovary Syndrome，PCOS）不同诊断标准共享遗传结构"一文所讨论的分析相关的数据。本文件中呈现的数据适用于任意诊断标准的分析，但排除了来自23andMe的自我报告型数据。本文件的表头字段如下：标记名称（MarkerName）、效应等位基因（Effect_allele）、其他等位基因（Other_allele）、等位基因频率（EAF）、效应值（Effect）、标准误（StdErr）、P值（Pvalue）、总样本量（TotalSampleSize）。本表格中报告的数据已被截断至两位有效数字。

搜集汇总

背景与挑战

背景概述

该数据集包含多囊卵巢综合征(PCOS)的大规模基因组元分析结果，提供了不同诊断标准下的遗传关联统计数据，包括基因标记、等位基因频率、效应大小等关键指标。数据采用开放获取许可，源自剑桥大学MRC流行病学单位的研究项目。