Treatment outcome in monkeys treated with DB844 while in second stage T. b. rhodesiense infection.
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Key: ID = identity in the laboratory; PP = pre-patent period; DPI = days post infection; CSF = cerebrospinal fluid; Tryps = trypanosomes; WC = white cells; EoT = end of treatment; ToC = test of cure; Neg = Negative; Pos = positive; WD = withdrawn from the experiment after 10th drug dose due to toxicity; Numbers in square brackets = maximum number of white cell counts observed during any of the four weekly samplings between 0–27 DPI; I: DB844 5 mg/kg×10 days per os; 28–37 DPI; II: DB844 6 mg/kg×14 days per os; 28–41 DPI.
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2015-12-02



