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82-kDa ChAT and SATB1 ChIP-seq after vehicle or amyloid-beta exposure

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP064320
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资源简介:
Using chromatin immunoprecipitation and next-generation sequencing (ChIP-seq), we assessed the effects of acute exposure to oligomeric amyloid-beta on 82-kDa ChAT and SATB1 genome association in human SH-SY5Y neural cells, finding that Aß-exposure increased 82-kDa ChAT and SATB1 association with gene promoters, introns and matrix attachment regions. We found that both SATB1 and 82-kDa ChAT associate with synapse and cell stress related genes after amyloid-beta exposure. Overall design: Examination of effects of amyloid-beta exposure on 82-kDa ChAT and SATB1 in human SH-SY5Y neural cells
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2017-09-17
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