Coupled myovascular expansion directs cardiac growth and regeneration
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=1ec3371f6f8f29f17a8dfe77b8ac0253
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Purpose: The goal of this experiment is to better understand the molecular mediators of myovascular coupling during growth and injury.Methods: We performed single cell RNA-sequencing (scRNA-Seq) of border zones of cryoinjured murine hearts collected at P7 using the Drop-seq protocol.Results: Together with in situ hybridization data, results from the scRNA-seq data analysis support a dynamic role for myocardial VEGFA to endothelial VEGFR2 signaling as a regulator of the myovascular expansion during growth and regeneration.
提供机构：
Duke University
创建时间：
2022-02-20
