MicroRNA 19a replacement partially rescues fin and cardiac defects in zebrafish model of Holt Oram syndrome [miRNA-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP059278
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资源简介:
The regulative role of miRNAs in Holt-Oram Syndrome is investigated in a zebrafish model. Overall design: The zebrafish gene Tbx5a was silenced with antisense morpholino oligonucleotide MO-Tbx5a against the TSS of the gene. A MO-CT was used in CT sample. 1.5ng morpholinos were injected into the yolk of 1-cell stage embryos and total RNA extracted from 50 embryos collected at 48hpf.The Zebrafish wild-type AB strain line was used.
创建时间:
2019-09-29



